The renaissance was also a halcyon period for painting and sculpture. The colossal triptych relating the legend of St. Stanisław (Stanislaus) in the Church of St. Stanisław in Kobylin was endowed by the Bishop of Cracow, Jan Konarski, c. 1518. The Kościan parish church, the Church of St. John in Krotoszyn, Smogulec (Wągrowiec County), and the Szamotuły Collegiate Church all have admirable late renaissance altars.

Mannerism, which later became prevalent in Poland, is represented by the works of painter and wood carver Mateusz Kossior (d. 1598). These are triptychs in form and can be found in Kłecko, most likely in Połajewo (Czarnków-Trzcianka County), and the Wągrowiec parish church (2 works).

Krzysztof Boguszewski (d. 1635) is the best known painter working in Wielkopolska during the transitional period between the renaissance and the baroque. He worked in the Cistercian monastery in Gościkowo (Świebodzin County), where such famous paintings as St. Martin and Blue Jerusalem were created. His works can be found in St. Wojciech’s Church in Poznań and in Poznań Cathedral. Wall paintings are considerably rarer. Examples include the polychrome fragments in the Ostrzeszów parish church and the polychromes in the wooden church in Tarnowo Pałuckie (Wągrowiec County) and the Chapel of Our Lady of the Rosary in the Wągrowiec parish church.